Heck yah!
It's just a variation on the old "Game of NIM".
If you google that phrase, you'll find a slew of sites offering techniques on how to win. You'll have to know how to convert to binary though . . .
It's not enough that he beats me, but he has to finish laughing before we start a new game... why, why me... why damnit why! can't sleep, man will eat me